Photodynamic therapy (PDT) – treat cancer cells with light


Modern laser therapy helps cancer patients at the Hyperthermia Center Hanover
Photodynamic therapy (PTD) is One of the most promising and gentle treatment approaches in biological cancer therapy: Tumor patients in the Hyperthermia Center in Hanover are now being treated with this relatively simple and gentle form of therapy consisting of a laser light in combination with different light-sensitive substances.

Photodynamic therapy (PDT) is a minimally invasive treatment option for various cancers. PDT refers to a method for treating tumors and other tissue changes (such as angiogenesis) with light in combination with a light-activated substance. “Compared to traditional chemotherapy, side effects hardly occur and the immune system is not burdened but activated,” says Dr. Peter Wolf, director of the Hyperthermia Center in Hanover. “This is an outstanding advantage for our patients.”

At the beginning of the treatment the patients are given light-sensitive substances (photosensitizers based on plant substances) intravenously (into the bloodstream). These natural substances accumulate in the cancer cells causing a strong sensitivity to light. The thus enriched tumor cells are then treated with laser light of a specific wavelength (ie, color), which triggers the photosensitizers to synthetize aggressive oxygen radicals within these cells which leads to their destruction. In contrast, the healthy cells remain unaffected by this chemical reaction.

In ophthalmology and dermatology, photodynamic therapy (PDT) is now used as a standard procedure. In oncology, compared with surgical treatment, the PDT offers the advantage of a non-invasive or minimally-invasive procedure. Particularly, the removal of healthy tissue surrounding a tumor (for safety reasons) is unnecessary. The use of photodynamic therapy (PDT) has been and is being studied scientifically – inter alia with prostate and bladder cancer (interstitial laser therapy) – and is therefore ideally suited to treat and destroy cancerous tissue in one treatment, without severe side effects, and depending on its size and location.

This photosentitizing agent can also penetrate parasites, bacteria and viruses, allowing them to be destroyed by light. Photodynamic laser therapy is thereby well suited for the treatment of antibiotic-resistant infections, MRSA (hospital germs), Lyme disease, hepatitis and multiple sclerosis. This is a further development of photodynamic laser therapy, which in the past was mainly applied as antibacterial photodynamic therapy notably in dentistry to destroy bacteria.

The blood irradiation is a special form of PDT during which laser light is guided via a catheter into the vein directly into the flowing blood. For a systemic biological cancer therapy, this blood-cleansing treatment can be done in a targeted tumor area. Almost all patients show a general stabilization, an energization and overall positive effects – even with chronic liver disease, diabetes mellitus, dyslipidemia and various other diseases as well as with parasites in the bloodstream.

The Hyperthermia Center Hanover, under the direction of Dr. Peter Wolf, is one of the largest providers of hyperthermia in Germany. For more than 30 years of integrative cancer therapy and biological therapy procedures, not only do they offer photodynamic therapy but various forms of hyperthermia (whole-body hyperthermia, locoregional hyperthermia and transurethral hyperthermia (hyperthermia of the prostate)) as well. Bioresonance, homeopathy, psychotherapy, acupuncture, galvanotherapy and insulin potentiation therapy (low-dose chemotherapy) complete the offer to a holistic therapy concept. The Hyperthermia Center in Hanover treats outpatients with a focus on regulation therapies, regenerative therapies and active biological cancer therapy.